After completing the game and getting all the endings, Tokyo can be selected in Free Exploration. Beating the level will reward the playing with a new dragon form, a Su-43 (or "????" in the game). It is a Strike Fighter used in Ace Combat 3.

Leonard's Faerie chose its boyish appearance as a reflection of Leonard's preferences.

The weapons "Takamasa" and "Nobuyoshi" were named after the game's producer, Takamasa Shiba, and composer, Nobuyoshi Sano.

According to Cavia producer, Takuya Iwasaki, Verdelet was originally going to be a boss character. However, the team realized that they lacked a person who was concerned for the Goddess and decided to adapt him for this position.

According to Takuya Iwasaki, the twins Seere and Manah were loosely based on Natalie Portman's twelve year old character in the film "Léon: The Professional".

According to creative directer, Taro Yoko, Arioch's character was roughly inspired by Ritsuko Akagi from Neon Genesis Evangelion, and was entirely his idea.

The weapon "Skald's Song" was originally known as the Devolapopola in the Japanese version of the game. The original version of the story included the names of the sisters, Dobo and Popo. This story was the main inspiration for the characters Devola and Popola in the spin-off Nier.

The world map is an upside-down map of Europe.

Inuart was originally intended to take the role of the game's protagonist, while Caim was going to be the rival character.

Yoko became director only because Iwasaki was too busy with other projects at the time. Yoko was originally planned to be the art director. Iwasaki and Shiba had no experience writing stories and were mainly driven to have as many game mechanics and content as possible over creative issues. Yoko considers Iwasaki the "true father" of the series.

Character designer, Kimihiko Fujisaka, has said in a Famitsu interview that he was embarrassed to see his designs from ten years ago and especially regretted Caim's design. When he redrew Caim for Lord of Vermillon, Fujisaka's main goal for his outfit was to do something which was impossible for the team to render during Drakengard's development.

A mobile port of the game was developed by Macrospace as part of a collaboration between Square Enix and Vodafone, designed to function on the Vodafone live! It was only released in Europe.

In the original Japanese release, the game contained themes surrounding the subjects of incest, cannibalism and pedophilia. These were either removed entirely or heavily downplayed when the title was brought over to the western market.

Taro Yoko had originally wanted the Red Dragon and Caim's relationship to be similar to a parasitic one, with the Dragon as being the "host". However, he admits he had no real hand in planning the main story fans are familiar with and feels odd calling Red the "true heroine" of the first game. Because of this, he could not relate to the popularity of the romantic relationship. In a write-in question for Dengeki Online's Drakengard 3 character popularity questionnaire, A personal question from Yoko appears, asking fans to explain the popularity of Caim and the Red Dragon's pairing to him.

The final ending is titled Spoiler:"The End of the Dragon Sphere". This is likely a reference to Drakengard's project name "Project Dragonsphere" or to The End of Evangelion, with the Spoiler:Queen-beast's death in the game strongly resembling Lilith's death scene in the anime.

Even though the Swordsmasher's magic attack, Pale Death, turns the wielder invisible, the enemy AI will still attack the player regardless.

Both Caim and Seere's names come from the 53rd and 70th demons from the Lesser Key of Solomon, a mid-seveteenth century grimoire on Demonology.

Furiae was originally conceptualized to be blonde and was going to be a more hidden figure throughout the story. The development team had claimed that she was only made for Caim and Inuart's rivalry, and her personality is roughly modeled after Rei Ayanami from Neon Genesis Evangelion. Taro Yoko had stated she is his take on the sisters from the Sister Princess series.

Caim's design was loosely based on Guts from Berserk. The weapon Hymir's Finer/Broken Iron is also a reference to Guts' weapon, Dragonslayer.

According to Taro Yoko, Leonard is roughly based off of Slegger Law from Mobile Suit Gundam.