Franchise: Command & Conquer
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Joe Kucan, the actor for Kane, wasn't originally going to have the role. Kucan created video footage of himself to use as a place holder for a scene, however his performance was positively received during play testing, and so he was kept on for the role.
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Command & Conquer was originally going to be in a fantasy setting, but was changed to a modern setting to better fit the political climate of the nineties and to make it more accessible to the public.