Many characters in the series are based on characters from history, pop culture, films and manga.

• Hanzo Hatori and Fuuma Kotaro are based on the legendary ninja of the same name from Japanese folklore.
• Rasputin is based on the infamous mad monk Grigori Rasputin.
• Janne D'Arc is based off of Joan of Arc.
• Jenghis Carn is based off of Genghis Kahn.
• Brocken is based off of the character of Stroheim from Part 2 of JoJo's Bizarre Adventure and Brocken Jr. from Kinnikuman.
• Kim Dragon is based off of Bruce Lee.
• Muscle Power is based off of Hulk Hogan.
• Geegus is based off the T-1000 from Terminator 2.
• Captain Kidd was based off of the infamous pirate Captain William Kidd.
• Erik is based off of Erick the Red.
• Johnny Maximum is loosely based off of American football player Joe Montana.
• Mud Man is based off the protagonist of Daijiro Morohoshi's manga "Mud Man".
• Ryoko Izumo is based on Japanese judoka Ryoko Tamura.
• Shura is based off of Muai Thai kickboxer Nai Khanom Tom.
• DIO is based heavily off of Kars and Dio Brando from JoJo's Bizarre Adventure and Baoh from the pre-araki manga of the same name.
• Ryofu is based off of Chinese warlord Lu Bu.
• Jack is based off of the infamous serial killer Jack the Ripper.
• Zeus is based off of Raoh from Fist of the North Star.
• Son Gokuu is based off of both Sun Wukong, his namesake, in Journey to the West and the version of Son Goku in Dragon Ball.