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Pokémon Puzzle League is the first Pokémon game to be released exclusively to the Western market, and not in Japan.
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Hidden inside the code are two unused voice clips. They are presumably from staff issuing a little message to loved ones, as one is in Japanese and reads "Yumi-chan, I love you" and the other reads "I love you Liz."
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In order to temporarily unlock Mewtwo in vs. mode, you must hold Z, and then press B, Up, L, B, A, Start, A, Up, R. The combination spells out "Bulbasaur".
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The version of Panel de Pon included on Nintendo Puzzle Collection was originally intended to be released on the Nintendo 64 in Japan, and a prototype featuring the Panel de Pon fairy characters is known to exist. It did see release on the console in other regions as Pokémon Puzzle League, however.
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