The "Sausage" and "Legendary Sausage" weapons in Holocure: Save the Fans! are based on the mobile games Sausage Legend and Sausage Legend 2, which are known for being played on livestreams by Hololive talent Oozora Subaru and her viewers. According to developer Kay Yu, he was granted permission by the Sausage Legend developers to reference the game via these weapons and its collaborations. In 2023, the references culminated in Hololive working with the Sausage Legend developers to release special skins for Sausage Legend 2 based on Subaru and fellow member Hakui Koyori.

The "X-Potato" weapon is a reference to one of Inugami Korone's livestreams of Blasphemous, in which she accidentally mispronounces the name Exposito while looking up boss names up after beating the game. It is unlocked by surviving 10 minutes while playing as Korone in a run. Its available Collabs (fusions between two weapons) are also references to Korone:

• Rap Dog (combined with Idol Song): Alludes to Korone's ability to rap, most prominently shown off when she and Nekomata Okayu sang "if..." by DA PUMP.
• MiKorone (combined with Elite Lava Bucket): A portmanteau of Inugami Korone and Sakura Miko's names, a term for streams featuring the two collaborating together.
• I'm Die, Thank You Forever (combined with Holo Bomb): References a collaboration between her and Mori Calliope played Keep Talking And Nobody Explodes, each using their non-native language (English for Korone and Japanese for Calliope). During one attempt, Korone, realizing she couldn't diffuse the bomb in time, uttered "Ah, I'm die, thank you forever" before exploding.

Both the Bounce Ball and Cutting Board items have different effects based on which character is using it. Specifically, they appear to be affected by bust size. For example, characters with larger chests (i.e. Tsukomo Sana, Ouro Kronii, Pavolia Reine) will spawn larger Bounce Balls. Conversely, characters labeled as being "flat chested" (i.e. Gawr Gura, Natsuro Matsuri, Kobo Kanaeru) will spawn larger projectiles when equipped with Cutting Board. Both these items, and their effects, reference former hololive member Uruha Rushia, who would get upset at people for teasing her flatness, insisting that she is actually "boing boing" (the Bounce Ball references this onomatopoeia).