According to a interview with ABC News, when Shigeru Miyamoto was asked why Daisy and Wario aren't a part of the main Mario titles, Miyamoto replied that "Both Daisy and Wario were originally drawn as part of the "Mario Land" games and had the same illustrator. The art style of those games was different from the "Mario World" series with Mario, Luigi and Princess Peach, and for a long time that was the reason that we didn't have those characters enter into each other's stories." This question and answer were removed in a later update to this article.

Despite this statement, Wario did appear in the DS update of Super Mario 64 and Mario faced off against the enemies of Wario Land 3 in Dr. Mario 64. This not only explains their absence in main Mario games, but also might explain the lack of direct representation of their games in the Mario spin off games in terms locations, enemies, characters, and special moves such as Wario's iconic shoulder bash.

Daisy would eventually be included in the main Mario games as a character added to the mobile game Super Mario Run in the Ver. 3.0.4 update, in addition to having a role in Super Mario Bros. Wonder.